Variation in recombination frequency and distribution across eukaryotes: patterns and processes. Sex-chromosome evolution: recent progress and the influence of male and female heterogamety. The human major histocompatibility complex as a paradigm in genomics research. Natural selection constrains neutral diversity across a wide range of species. Recombination drives vertebrate genome contraction. Mammalian meiotic recombination: a toolbox for genome evolution. Meiotic recombination and genome evolution in plants. Recombination rate variation and speciation: theoretical predictions and empirical results from rabbits and mice.
The barrier to genetic exchange between hybridising populations. Recombination rate variation shapes barriers to introgression across butterfly genomes. Natural selection interacts with recombination to shape the evolution of hybrid genomes. Biased gene conversion and the evolution of mammalian genomic landscapes. Biased inference of selection due to GC-biased gene conversion and the rate of protein evolution in flycatchers when accounting for it. Elevated mutation rate during meiosis in Saccharomyces cerevisiae. Recombination load associated with selection for increased recombination. Recombination modification in a fluctuating environment. Evolution of sex: experimental tests of the adaptive significance of sexual recombination. This article describes mathematical models of how recombination evolves via selection on recombination modifiers. A general model for the evolution of recombination. Highly variable recombinational landscape modulates efficacy of natural selection in birds. This article presents the theory describing the behaviour of two linked loci under selection. The effect of linkage on limits to artificial selection. The ecology and evolutionary dynamics of meiotic drive. Background selection as null hypothesis in population genomics: insights and challenges from Drosophila studies. Regions of lower crossing over harbor more rare variants in African populations of Drosophila melanogaster. The evolutionary advantage of recombination. This review compares the different recombination inference methods (linkage disequilibrium-based, pedigree-based, sperm-typing and hotspot detection) in humans where the most extensive data are available.įelsenstein, J. Contrasting methods of quantifying fine structure of human recombination. This review emphasizes population-level variation in recombination rates and discusses the potential molecular constraints and evolutionary processes underlying this variation.Ĭlark, A. Variation in recombination rate: adaptive or not? Trends Genet. Recombination: the good, the bad and the variable. Recombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans. A change of view: homologous recombination at single-molecule resolution. Evolution of sex: resolving the paradox of sex and recombination.
This influential perspective article discusses the variation in recombination, theoretical expectations and its importance for speciation. Recombination speeds adaptation by reducing competition between beneficial mutations in populations of Escherichia coli. Recombination rate evolution and the origin of species. Origins of the machinery of recombination and sex.
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